Charity<p> <strong>Welcome to the Charity Community</strong></p><p>The structure of collections and items within this communityrepresents a typical selection of items from charities</p>http://hdl.handle.net/2384/2946182024-03-28T13:56:35Z2024-03-28T13:56:35ZDigitoxin metabolism by rat liver microsomes@1.http://hdl.handle.net/2384/3445362022-10-25T12:55:13Z1975-09-01T00:00:00ZDigitoxin metabolism by rat liver microsomes@1.
1. Crude extracts and partially purified enzyme preparations from potato tubers catalyse, at pH 5-7, the conversion of linoleic acid hydroperoxides to a range of oxygenated fatty acid derivatives. 2. 9-D- and 13-L-hydroperoxide isomers are converted at similar rates to equivalent (isomeric) products. 3. The major products from the 13-hydroperoxide isomer were identified as the corresponding monohydroxydienoic acid derivative, threo-11-hydroxy-trans12,13-epoxy-octadec-cis9-enoic acid and 9,12,13-trihydroxy-octadec-trans10-enoic acid. The corresponding products from the 9-hydroperoxide were the monohydroxydienoic acid, 9,10-epoxy-11-hydroxy-octadec-12-enoic acid and 9,10,13-trihydroxy-octadec-11-enoic acid. 4. No separation of activities forming the different products was achieved by partial purification of enzyme extracts. 5. Product formation was unaffected by EDTA, CN-, sulphydryl reagents or glutathione but was reduced by boiling the extracts. 6. This system is compared with the 9-hydroperoxide-specific enzymic formation of divinyl ether derivatives by potato extracts.
1975-09-01T00:00:00ZPLAN-S Compliant Test Item: Publishing peer review materialsBeck, JeffreyFunk, KathrynHarrison, MelissaMcEntyre, JoBreen, JosieCollings, AndyDonohoe, PaulEvans, MichaelFlintoft, LouisaHamelers, AudreyHurst, PhilLemberger, ThomasLin, JenniferO'Connor, NiamhParkin, MichaelParker, SamRodgers, PeterSkipper, MagdalenaStoner, Michaelhttp://hdl.handle.net/2384/5828512019-08-30T13:47:03Z2018-01-01T00:00:00ZPLAN-S Compliant Test Item: Publishing peer review materials
Beck, Jeffrey; Funk, Kathryn; Harrison, Melissa; McEntyre, Jo; Breen, Josie; Collings, Andy; Donohoe, Paul; Evans, Michael; Flintoft, Louisa; Hamelers, Audrey; Hurst, Phil; Lemberger, Thomas; Lin, Jennifer; O'Connor, Niamh; Parkin, Michael; Parker, Sam; Rodgers, Peter; Skipper, Magdalena; Stoner, Michael
Publishing peer review materials alongside research articles promises to make the peer review process more transparent as well as making it easier to recognise these contributions and give credit to peer reviewers. Traditionally, the peer review reports, editors letters and author responses are only shared between the small number of people in those roles prior to publication, but there is a growing interest in making some or all of these materials available. A small number of journals have been publishing peer review materials for some time, others have begun this practice more recently, and significantly more are now considering how they might begin. This article outlines the outcomes from a recent workshop among journals with experience in publishing peer review materials, in which the specific operation of these workflows, and the challenges, were discussed. Here, we provide a draft as to how to represent these materials in the JATS and Crossref data models to facilitate the coordination and discoverability of peer review materials, and seek feedback on these initial recommendations.
2018-01-01T00:00:00Zarticle itemhttp://hdl.handle.net/2384/5827922021-09-27T14:25:38Z2017-06-20T00:00:00Zarticle item
2017-06-20T00:00:00Ztesthttp://hdl.handle.net/2384/5827912019-08-23T09:45:28Z2017-06-08T00:00:00Ztest
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