Recent Submissions

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    Unknown author (2017-06-20)
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    Unknown author (2017-06-08)
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    University of South (2017-06-08)
  • Digitoxin metabolism by rat liver microsomes.

    Schmoldt, A; Benthe, H F; Haberland, G; Sanchez, G; Alderete, J F; Bridgewater, S; Camp, H M; Hendrickson, W A; Ward, K B; Galliard, T; Phillips, D R; Matthew, J A; Bundy, CL (1975-09-01)
    1. Crude extracts and partially purified enzyme preparations from potato tubers catalyse, at pH 5-7, the conversion of linoleic acid hydroperoxides to a range of oxygenated fatty acid derivatives. 2. 9-D- and 13-L-hydroperoxide isomers are converted at similar rates to equivalent (isomeric) products. 3. The major products from the 13-hydroperoxide isomer were identified as the corresponding monohydroxydienoic acid derivative, threo-11-hydroxy-trans12,13-epoxy-octadec-cis9-enoic acid and 9,12,13-trihydroxy-octadec-trans10-enoic acid. The corresponding products from the 9-hydroperoxide were the monohydroxydienoic acid, 9,10-epoxy-11-hydroxy-octadec-12-enoic acid and 9,10,13-trihydroxy-octadec-11-enoic acid. 4. No separation of activities forming the different products was achieved by partial purification of enzyme extracts. 5. Product formation was unaffected by EDTA, CN-, sulphydryl reagents or glutathione but was reduced by boiling the extracts. 6. This system is compared with the 9-hydroperoxide-specific enzymic formation of divinyl ether derivatives by potato extracts.
  • The Warwick-Edinburgh Mental Well-being Scale (WEMWBS): development and UK validation

    Tennant, Ruth; Hiller, Louise; Fishwick, Ruth; Platt, Stephen; Joseph, Stephen; Weich, Scott; Parkinson, Jane; Secker, Jenny; Stewart-Brown, Sarah (27/01/2015)
  • Toxin-antitoxin based transgene expression in mammalian cells

    Nehlsen, K.; Herrmann, S.; Zauers, J.; Hauser, H.; Wirth, D. (2013-08-02)
  • Generation of Human Antigen-Specific Monoclonal IgM Antibodies Using Vaccinated “Human Immune System” Mice

    Becker, Pablo D.; Legrand, Nicolas; van Geelen, Caroline M. M.; Noerder, Miriam; Huntington, Nicholas D.; Lim, Annick; Yasuda, Etsuko; Diehl, Sean A.; Scheeren, Ferenc A.; Ott, Michael; Weijer, Kees; Wedemeyer, Heiner; Di Santo, James P.; Beaumont, Tim; Guzman, Carlos A.; Spits, Hergen; Unutmaz, Derya (01/08/2013)
  • Extreme Weather Events and Crop Price Spikes in a Changing Climate: Illustrative global simulation scenarios

    Willenbockel, Dirk (Oxfam International, 05/09/2012)
    Agriculture is highly sensitive to climate variability and weather extremes. Various impact studies have considered the effects of projected long-run trends in temperature, precipitation and CO2 concentrations caused by climate change on global food production and prices. But an area that remains underexplored is the food price impacts that may result from an expected increase in the frequency and intensity of extreme weather events. This study uses a global dynamic multi-region computable general equilibrium (CGE) model to explore the potential food price impacts of a number of extreme weather event scenarios in 2030 for each of the main exporting regions for rice, maize and wheat.
  • Squeezed: Life in a Time of Food Price Volatility, Year 1 results

    Hossain, Naomi; King, Richard; Kelbert, Alexandra (Institute of Development Studies, University of Sussex, 23/05/2013)
    Half a decade after the price spike of 2007-2008, food price volatility has become the new norm: people have come to expect food prices to rapidly rise and fall, though nobody knows by how much or when. So what does the accumulation of food price rises mean for well-being and development in developing countries? And what can be done to improve life in a time of food price volatility? Squeezed provides some preliminary answers to these big development questions, based on the first year results of a four-year project conducted across 10 countries with different levels of exposure to price rises. While high and rising food prices no longer come as a surprise, rapid price changes and the cumulative effects of five years’ worth of price rises are still squeezing those on low incomes. In areas of life neglected by policy – especially domestic care work and informal social safety nets – Squeezed provides reasons to prepare for the next food price spike and provides recommendations for how best to do so, including: widening social assistance for the most vulnerable; being ready with temporary spike-proofing measures; monitoring the real impacts on people’s lives and wellbeing; rethinking social protection policy to ‘crowd-in’ care and informal social assistance; and enabling people to participate in policies to tackle food price volatility.
  • Walking the Breadline: The scandal of food poverty in 21st-century Britain

    Cooper, Niall; Dumpleton, Sarah (Church Action on Poverty, 30/05/2013)
    Although the UK is the seventh richest country in the world, many people struggle to afford even the most essential of goods: food. In this briefing, Church Action on Poverty and Oxfam highlight the rise in food poverty in the UK, where over 500,000 are now thought to be reliant on food parcels. Figures from the Trussell Trust, the biggest network of foodbanks in the UK, reveal that cuts and changes to the welfare system are the most common reason for people resorting to food banks. This growth in food aid demonstrates that the social safety net is failing. Church Action on Poverty and Oxfam believe that everyone should have enough income to feed themselves and their families with dignity, and that foodbanks should not replace the social safety net. This is why we are recommending, among other things, that the government conducts an urgent inquiry into the relationship between welfare changes and cuts, and the growth of food poverty.
  • Managing Price Risk in Local Food Reserves: Analysing the prospects for a stabilisation fund in Mali and Niger

    Alba, Martin; Serra, Teresa; Gil, José María (Oxfam International, 05/07/2013)
    Local food reserves can contribute to food security strategies and have the potential to empower communities. These collective initiatives are set up and owned by small-scale producers with the objective of increasing the availability and access to food, or of increasing income by managing the food-price cycle. But the rate of failure among local food reserves is high, largely as a result of climate and price risks, coupled with challenges linked to their design, planning and management This research report analyses the possibility of developing a stabilisation fund as an effective price risk management tool to help local food reserves overcome their vulnerability to price cycle inversions. Four scenarios were considered and modelled on the basis of price data in a series of 12 cereal markets in Mali and Niger over a 15-year time span. The report concludes that the type of stabilisation fund outlined could represent a viable way of managing price risk in countries where the option of using market-based tools to tackle price risk is not available.
  • Economic Analysis of the Impact of Climate Change on Agriculture in Russia

    Safonov, Georgiy; Safonova, Yulia (BioMed Central, 01/04/2013)
    Climate Change
  • Review of Humanitarian Advocacy in Liberia and Ivory Coast during the Ivorian Crisis

    Jones, Brandy; Diouf, Alexandre (Oxfam GB, 2011-12-01)
    This report is part of learning activities undertaken by Oxfam’s West Africa Regional Office in order to improve the way that it conducts future advocacy campaigns during humanitarian crises in the region. Oxfam implemented an advocacy program in both Ivory Coast and Liberia. In both countries the advocacy work addressed the aftermath of the post-electoral crisis in Ivory Coast. In response to this crisis, Oxfam launched an ambitious campaign to strengthen the humanitarian response by addressing the needs of the hundreds of thousands of displaced people and those threatened by the fallout from the political conflict in the Ivory Coast. Oxfam’s role during the crisis was critical and important, the agency served as a leader for its peers. Not only conducting direct interventions in the sectors of water and sanitation, livelihoods, shelter and protection, Oxfam set themselves apart by working collaboratively with peer organizations to advocate and lobby for an improved and better coordinated effort.
  • Effectiveness Review: Routes to Solidarity, England

    Cambridge Policy Consultants (Oxfam GB, 2012-10-16)
    Oxfam's Routes to Solidarity project, launched in April 2009, seeks to empower Black and Minority Ethnic (BME) women and women’s groups by strengthening their organisational capacity and networking skills. This work is accompanied by efforts to ensure policy-makers are better informed and are putting in place policy solutions that benefit BME communities in England. This report documents the findings of a qualitative impact evaluation, carried out in March 2012, which used process tracing to assess the effectiveness of Routes to Solidarity's project in light of six targeted policy and practice changes identified by BME women themselves .
  • Effectiveness Review: Enhancing Access and Control to Sustainable Livelihood Assets, Philippines

    Hughes, Karl (Oxfam GB, 2012-10-08)
    The Enhancing Access and Control to Sustainable Livelihood Assets of the Manobo Tribe through Improved and Strengthened Self-governance of the Ancestral Territory programme is being implemented by Oxfam’s partner organisation, Paglilingkod Batas Pangkapatiran Foundation Incorporated (PBPF). The project aims is to improve household food security and empower women among a group of indigenous peoples that reside in a mountainous area that make up the Manobo-Mamanua Ancestral Domain. These full and summary reports document the findings of a quasi-experimental impact evaluation of this project carried out in March 2011.
  • Effectiveness Review: Food Security and Livelihoods Support among Fishers and Fish Processors, Democratic Republic of Congo

    Fuller, Rob (Oxfam GB, 2013-04-22)
    Oxfam GB carried out a food security and livelihoods programme in the area of Kasenyi and Tchomia, beside Lake Albert in the north-east of the Democratic Republic of Congo, from December 2008 to November 2009. In early 2012, a quasi-experimental evaluation was carried out to determine whether the impact of this work had been sustained. These reports document the findings of this process.
  • South Sudan Emergency Response in Maban County, Upper Nile State: Mid-Term Review Summary

    Unknown author (Oxfam GB, 2013-04-04)
    Since becoming independent on 9 July 2011, South Sudan has faced many challenges. Poor harvests have led to severe food shortages, and there have been continuous conflicts across the border with Sudan. In September 2011, intense fighting broke out in the Blue Nile State of Sudan between the Sudan Armed Forces and the Sudan People’s Liberation Army (North). Thousands of people fled the fighting, and over 30,000 refugees arrived in the camps in Jamam, a village in the remote Upper Nile State of South Sudan. Since November 2011, Oxfam and other humanitarian agencies have been responding to emergency needs of refugees displaced from Blue Nile. Drawing on an independent review, this summary report reviews the speed and quality of Oxfam’s intervention in the first seven and a half months of 2012, and responds to questions raised by other humanitarian actors including UNHCR and MSF about its performance. The aim of this summary is to contribute to organisational learning on the implementation of humanitarian interventions. It acknowledges Oxfam’s achievements, but also addresses challenges about the nature of its response. The summary draws together key points to aid understanding of the context of this programme, and critically examines what Oxfam and others could do differently to deliver rapid, good-quality emergency WASH programmes in the future. It summarises findings from an independent review, and makes recommendations for policy and practice that could have enhanced the Maban response, and will help to improve the quality of further programmes by Oxfam and other agencies working in complex, fragile environments.
  • The Politics of Our Lives: The Raising Her Voice in Pakistan Experience

    Repila, Jacky (Oxfam GB, 2013-07-04)
    How can we change the power dynamics that exclude women from decision making? How can the barriers that prevent women from exercising their rights as equals to lead, to propose and to call to account be overcome? Over the past five years, the Raising Her Voice (RHV) programme set out to find practical answers to these questions. In the process, more than 700,000 women in 17 countries have benefitted from the results. This report looks at the experiences of the RHV programme in Pakistan, a complex and sensitive context, where women activists face both great opportunities and immense challenges. Working in partnership with the Aurat Foundation (AF), the RHV programme organized 1,500 women activists, living and working in their communities, into ‘50 Women Leaders Groups’ (WLGs) in 30 districts across Pakistan. The aims of the WLGs were: to promote activism within their communities; to defend and promote women’s rights; to represent marginalized women; and to raise women’s collective voice at local and district levels, as well as, with AF’s support, at the provincial and national level. As the RHV programme draws to a close, the experiences and achievements of the WLGs, with their strong national partnership and focus of community level activism, contain valuable insights for anybody working to promote women’s political participation and leadership in volatile and complex environments.

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